Cannabinoid THC has been found to have a protective effect on aging brains by helping them to clear out toxic clumps of an Alzheimer’s protein. This post from Science Alert highlights how this could turn out to be huge. An active compound in marijuana called tetrahydrocannabinol (THC) has been found to promote the removal of toxic clumps of amyloid beta protein in the brain, ... Continue Reading
neuroprotective
STUDY: An exploration of the potential mechanisms and translational potential of five medicinal plants for applications in Alzheimer’s disease
ABSTRACT: Alzheimer’s disease (AD) is the most common type of dementia, and represents a vast worldwide socio-economic burden, and in the absence of a current cure, effective therapeutic strategies are still needed. Cholinergic and cerebral blood flow deficits, excessive levels of oxidative stress, neuroinflammation and glutamate excitatory mechanisms are all believed to ... Continue Reading
STUDY: The endocannabinoid system as a target for the treatment of neurodegenerative disease
ABSTRACT: The Cannabis sativa plant has been exploited for medicinal, agricultural and spiritual purposes in diverse cultures over thousands of years. Cannabis has been used recreationally for its psychotropic properties, while effects such as stimulation of appetite, analgesia and anti-emesis have lead to the medicinal application of cannabis. Indeed, reports of medicinal ... Continue Reading
STUDY: Neuroprotective and Blood-Retinal Barrier-Preserving Effects of Cannabidiol in Experimental Diabetes
ABSTRACT: Diabetic retinopathy is characterized by blood-retinal barrier (BRB) breakdown and neurotoxicity. These pathologies have been associated with oxidative stress and proinflammatory cytokines, which may operate by activating their downstream target p38 MAP kinase. In the present study, the protective effects of a nonpsychotropic cannabinoid, cannabidiol (CBD), were ... Continue Reading