ABSTRACT: The cannabinoid receptor 1 (CB1) and CB2 cannabinoid receptors, associated with drugs of abuse, may provide a means to treat pain, mood, and addiction disorders affecting widespread segments of society. Whether the orphan G-protein coupled receptor GPR55 is also a cannabinoid receptor remains unclear as a result of conflicting pharmacological studies. GPR55 has ... Continue Reading
cannabis dependence
STUDY: Non-Smoker Exposure to Secondhand Cannabis Smoke. I. Urine Screening and Confirmation Results
ABSTRACT: Increased cannabis potency has renewed concerns that secondhand exposure to cannabis smoke can produce positive drug tests. A systematic study was conducted of smoke exposure on drug-free participants. Six experienced cannabis users smoked cannabis cigarettes (5.3% THC in Session 1 and 11.3% THC in Sessions 2 and 3) in a sealed chamber. Six non-smokers were seated ... Continue Reading
Who Is at Higher Risk for Cannabis Addiction?
Scientists have identified the genes that predispose people to cannabis addiction. This post from the Daily Beast highlights that the pot dependence genes are also linked to schizophrenia and depression. According to new research, you don’t sit around in sweatpants andsmoke pot simply because you’re lazy. Such a habit could be the result of a genetic inheritance. It’s your ... Continue Reading
STUDY: Why should Cannabis be Considered Doping in Sports?
ABSTRACT: Recent debate and cases involving elite athletes raised the question whether or not Cannabis sativa (cannabis) should be considered doping in sports. Results from a 2010 report in the United States (Substance Abuse and Mental Health Services Administration,2011) showed that cannabis is the most used illicit drug, with 17.4 million users smoking cannabis and 6.9 ... Continue Reading
STUDY: Adverse effects of medical cannabinoids: a systematic review
ABSTRACT: Background The therapeutic use of cannabis and cannabis-based medicines raises safety concerns for patients, clinicians, policy-makers, insurers, researchers and regulators. Although the efficacy of cannabinoids is being increasingly demonstrated in randomized controlled trials, most safety information comes from studies of recreational use. Methods We ... Continue Reading