ABSTRACT: The endocannabinoid system is implicated in a variety of physiological and pathological conditions (inflammation, immunomodulation, analgesia, cancer and others). The main active ingredient of cannabis, Δ9-tetrahydrocannabinol (Δ9-THC), produces its effects through activation of CB1 and CB2 receptors. CB1 receptors are expressed at high levels in the central nervous ... Continue Reading
clinical trial
STUDY: Preliminary efficacy and safety of an oromucosal standardized cannabis extract in chemotherapy-induced nausea and vomiting
ABSTRACT: AIMS Despite progress in anti-emetic treatment, many patients still suffer from chemotherapy-induced nausea and vomiting (CINV). This is a pilot, randomized, double-blind, placebo-controlled phase II clinical trial designed to evaluate the tolerability, preliminary efficacy, and pharmacokinetics of an acute dose titration of a whole-plant cannabis-based medicine ... Continue Reading
Government Denies Access to CBD for Potentially Life-Saving Treatment
In this post Itamar Shapira of Huntsville, a 2014 graduate in biomedical engineering, talks about his medical conditions and the struggles he faces during an interview in downtown Huntsville, Ala. Tuesday, Aug. 26, 2014. WHAT RIGHT DOES THE GOVERNMENT HAVE TO DENY CANNABIS OIL TREATMENT TO SICK PEOPLE WHO NEED IT?: GUEST OPINION An article on 14 September featured my ... Continue Reading