ABSTRACT: Aims/hypothesis Recent studies have demonstrated that cannabinoid-1 (CB1) receptor blockade ameliorated inflammation, endothelial and/or cardiac dysfunction, and cell death in models of nephropathy, atherosclerosis and cardiomyopathy. However the role of CB1receptor signalling in diabetic retinopathy remains unexplored. Using genetic deletion or pharmacological ... Continue Reading
ICAM-1
STUDY: Cannabinoid 1 receptor activation contributes to vascular inflammation and cell death in a mouse model of diabetic retinopathy and a human retinal cell line
ABSTRACT: Aims/hypothesis Recent studies have demonstrated that cannabinoid-1 (CB1) receptor blockade ameliorated inflammation, endothelial and/or cardiac dysfunction, and cell death in models of nephropathy, atherosclerosis and cardiomyopathy. However the role of CB1receptor signalling in diabetic retinopathy remains unexplored. Using genetic deletion or pharmacological ... Continue Reading