THCA, like its better-known cousins CBD and THC, has numerous medicinal benefits. This post from marijuana.com turns the spotlight on this non-psychoactive cannabinoid. Recently, many patients have been asking me if they should be using THCA (tetrahydrocannabinolic acid), and if you have been paying attention, you may have seen products labeled “THCA” in your local ... Continue Reading
nonpsychoactive
STUDY: The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis
ABSTRACT: The therapeutic potential of cannabidiol (CBD), the major nonpsychoactive component of cannabis, was explored in murine collagen-induced arthritis (CIA). CIA was elicited by immunizing DBA/1 mice with type II collagen (CII) in complete Freund's adjuvant. The CII used was either bovine or murine, resulting in classical acute CIA or in chronic relapsing CIA, ... Continue Reading
STUDY: Emesis – The Nonpsychoactive Cannabinoid Cannabidiol Inhibits 5-Hydroxytryptamine3A Receptor-Mediated Currents in Xenopus laevis Oocytes
ABSTRACT: The effect of the plant-derived nonpsychotropic cannabinoid, cannabidiol (CBD), on the function of hydroxytryptamine (5-HT)3A receptors expressed in Xenopus laevis oocytes was investigated using two-electrode voltage-clamp techniques. CBD reversibly inhibited 5-HT (1 μM)-evoked currents in a concentration-dependent manner (IC50 = 0.6 μM). CBD (1 μM) did not ... Continue Reading