Confusion surrounds phytocannabinoids as most are not even aware of the rich spectrum of cannabinoids that lie beyond CBD. Get comfortable with phytocannabinoids in this post from Whole Foods Magazine! Many people believe in hemp. For food, culinary oil and even textiles hemp has become a big part of the natural products industry. However, where it stands in the dietary ... Continue Reading
phytocannabinoids
STUDY: Sativex-like Combination of Phytocannabinoids is Neuroprotective in Malonate-Lesioned Rats, an Inflammatory Model of Huntington’s Disease: Role of CB1 and CB2 Receptors
ABSTRACT: We have investigated whether a 1:1 combination of botanical extracts enriched in either Δ9-tetrahydrocannabinol (Δ9-THC) or cannabidiol (CBD), which are the main constituents of the cannabis-based medicine Sativex, is neuroprotective in Huntington’s disease (HD), using an experimental model of this disease generated by unilateral lesions of the striatum with the ... Continue Reading
STUDY: Pain – Evaluation of Prevalent Phytocannabinoids in the Acetic Acid Model of Visceral Nociception
ABSTRACT: Considerable preclinical research has demonstrated the efficacy of Δ9-tetrahydrocannabinol (Δ9-THC), the primary psychoactive constituent of Cannabis sativa, in a wide variety of animal models of pain, but few studies have examined other phytocannabinoids. Indeed, other plant-derived cannabinoids, including cannabidiol (CBD), cannabinol (CBN), and cannabichromene ... Continue Reading
STUDY: Obesity – Synthetic and plant-derived cannabinoid receptor antagonists show hypophagic properties in fasted and non-fasted mice
ABSTRACT: Background and purpose: Obesity is a severe health problem in the modernized world and understanding the central nervous mechanisms underlying food-seeking behaviour and reward are at the forefront of medical research. Cannabinoid receptors have proven an efficient target to suppress hunger and weight gain by their pharmacological inactivation. Experimental ... Continue Reading
STUDY: The Endocannabinoid System, Cannabinoids, and Pain
ABSTRACT: The endocannabinoid system is involved in a host of homeostatic and physiologic functions, including modulation of pain and inflammation. The specific roles of currently identified endocannabinoids that act as ligands at endogenous cannabinoid receptors within the central nervous system (primarily but not exclusively CB1 receptors) and in the periphery (primarily ... Continue Reading