ABSTRACT: Cannabidiol (CBD) is a natural non-psychotropic cannabinoid from marijuana (Cannabis sativa) with anti-epileptic and anti-inflammatory properties. Effect of CBD on naïve immune system is not precisely understood. In this study, we observed that administering CBD into naïve mice triggers robust induction of CD11b+Gr-1+ MDSC in the peritoneum, which expressed ... Continue Reading
PPARγ
STUDY: Receptors and Channels Targeted by Synthetic Cannabinoid Receptor Agonists and Antagonists
ABSTRACT: It is widely accepted that non-endogenous compounds that target CB1 and/or CB2receptors possess therapeutic potential for the clinical management of an ever growing number of disorders. Just a few of these disorders are already treated with Δ9-tetrahydrocannabinol or nabilone, both CB1/CB2 receptor agonists, and there is now considerable interest in expanding the ... Continue Reading