ABSTRACT: Cannabidiol (CBD) is a natural non-psychotropic cannabinoid from marijuana (Cannabis sativa) with anti-epileptic and anti-inflammatory properties. Effect of CBD on naïve immune system is not precisely understood. In this study, we observed that administering CBD into naïve mice triggers robust induction of CD11b+Gr-1+ MDSC in the peritoneum, which expressed ... Continue Reading
Epilepsy
CBD Reduced Seizures in Epileptic Children by 40%
A CBD-based treatment for LGS patients, including children, was shown to decrease seizures by about 40%. This post from Futurism shares more details of the CBD study. IN BRIEF A clinical study showed that a cannabis-based medication could benefit patients, including children, who suffer from a type of epilepsy known as LGS. The results showed that LGS patients who ... Continue Reading
STUDY: Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders
ABSTRACT: Objective To present a summary of current scientific evidence about the cannabinoid, cannabidiol (CBD) with regards to their relevance to epilepsy and other selected neuropsychiatric disorders. Methods We summarize the presentations from a conference in which invited participants reviewed relevant aspects of the physiology, mechanisms of action, ... Continue Reading
STUDY: Slim Evidence for Cannabinoids for Epilepsy
ABSTRACT: BACKGROUND: Marijuana appears to have anti-epileptic effects in animals. It is not currently known if it is effective in patients with epilepsy. Some states in the United States of America have explicitly approved its use for epilepsy. OBJECTIVES: To assess the efficacy of marijuana, or one of marijuana's constituents in the treatment of people with epilepsy. SEARCH ... Continue Reading
STUDY: Systematic review: Efficacy and safety of medical marijuana in selected neurologic disorders
ABSTRACT: Objective: To determine the efficacy of medical marijuana in several neurologic conditions. Methods: We performed a systematic review of medical marijuana (1948–November 2013) to address treatment of symptoms of multiple sclerosis (MS), epilepsy, and movement disorders. We graded the studies according to the American Academy of Neurology ... Continue Reading