ABSTRACT: The cannabis plant (Cannabis sativa) has been known by many names but the question remains ‘Can we call it medicine?' There has been renewed interest in the value of cannabis for the control of neuroinflammatory conditions such as multiple sclerosis, where it has been shown to have some effect on spasticity and pain both experimentally and in clinical trials in ... Continue Reading
Inflammation
STUDY: Autoimmune Disease – Do Cannabinoids have a therapeutic role in transplantation?
ABSTRACT: Cannabinoids have emerged as powerful drug candidates for the treatment of inflammatory and autoimmune diseases due to their immunosuppressive properties. While significant clinical and experimental data on the use of cannabinoids as anti-inflammatory agents exist in many autoimmune disease settings, virtually no studies have been performed on their potential role ... Continue Reading
STUDY: Cannabinoids as novel anti-inflammatory drugs
ABSTRACT: Cannabinoids are a group of compounds that mediate their effects through cannabinoid receptors. The discovery of Δ9-tetrahydrocannabinol (THC) as the major psychoactive principle in marijuana, as well as the identification of cannabinoid receptors and their endogenous ligands, has led to a significant growth in research aimed at understanding the physiological ... Continue Reading
STUDY: Alternative targets within the endocannabinoid system for future treatment of gastrointestinal diseases
ABSTRACT: Many beneficial effects of herbal and synthetic cannabinoids on gut motility and inflammation have been demonstrated, suggesting a vast potential for these compounds in the treatment of gastrointestinal disorders. These effects are based on the so-called ‘endocannabinoid system’ (ECS), a cooperating network of molecules that regulate the metabolism of the body’s ... Continue Reading
STUDY: Cannabinoid receptor 2: Potential role in immunomodulation and neuroinflammation Review
ABSTRACT: An accumulating body of evidence suggests that endocannabinoids and cannabinoid receptors type 1 and 2 (CB1, CB2) play a significant role in physiologic and pathologic processes, including cognitive and immune functions. While the addictive properties of marijuana, an extract from the Cannabis plant, are well recognized, there is growing appreciation of the ... Continue Reading