ABSTRACT: Cannabidiol (CBD) is a phytocannabinoid with therapeutic properties for numerous disorders exerted through molecular mechanisms that are yet to be completely identified. CBD acts in some experimental models as an anti-inflammatory, anticonvulsant, anti-oxidant, anti-emetic, anxiolytic and antipsychotic agent, and is therefore a potential medicine for the treatment ... Continue Reading
Ischemia
STUDY: Evaluation of the role of the cannabidiol system in an animal model of ischemia/reperfusion kidney injury
ABSTRACT: Objective This work aimed to investigate the effects of the administration of cannabidiol in a kidney ischemia/reperfusion animal model. Methods Kidney injury was induced by 45 minutes of renal ischemia followed by reperfusion. Cannabidiol (5mg/kg) was administered immediately after reperfusion. Results Ischemia/reperfusion increased the IL-1 and ... Continue Reading