ABSTRACT: Polycystic kidney disease (PKD) 2L1 protein is a member of the transient receptor potential (TRP) ion channel family. In circumvallate and foliate papillae, PKD2L1 is coexpressed with PKD1L3. PKD2L1 and PKD1L3 interact through their transmembrane domain and the resulting heteromer PKD1L3/PKD2L1 owns a unique channel property called ‘off-responses’ to acid ... Continue Reading
STUDY: The response of PKD1L3 / PKD2L1 to acid stimuli is inhibited by capsaicin and its pungent analogs
