ABSTRACT: Δ9-tetrahydrocannabinol (THC) produces varying effects in mesenteric arteries: vasorelaxation (third-order branches, G3), modest vasorelaxation (G2), no effect (G1) and vasoconstriction (the superior mesenteric artery, G0). In G3, vasorelaxation to THC was inhibited by pertussis toxin, but was unaffected by the CB1 receptor antagonist, AM251 (1 μm), ... Continue Reading
cannabinoid studies
STUDY: Human Cannabinoid Pharmacokinetics
A multitude of roles for the endogenous cannabinoid system has been proposed by recent research efforts. A large number of endogenous cannabinoid neurotransmitters or endocannabinoids have been identified, and the CB-1 and CB-2 cannabinoid receptors have been characterized. The presence of other receptors, transporters, and enzymes responsible for the synthesis or metabolism of ... Continue Reading
The 5 Most Exciting Cannabinoid Studies and Stories of 2015
2015 has seen an unprecedented number of cannabinoid studies, with interesting and positive outcomes for human health. This post from Marijuana.com puts together the 5 most significant cannabinoid studies of this year, till date. With just over two months to go before we ring in 2016, this has been another stealer year for cannabinoid research. One in which countless studies ... Continue Reading