ABSTRACT: Cannabidiol (CBD), a major non-psychotropic constituent of fiber-type cannabis plant, has been reported to possess diverse biological activities, including anti-proliferative effect on cancer cells. Although CBD is obtained from non-enzymatic decarboxylation of its parent molecule, cannabidiolic acid (CBDA), few studies have investigated whether CBDA itself is ... Continue Reading
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STUDY: The orphan receptor GPR55 is a novel cannabinoid receptor
ABSTRACT: Background: The endocannabinoid system functions through two well characterized receptor systems, the CB1 and CB2receptors. Work by a number of groups in recent years has provided evidence that the system is more complicated and additional receptor types should exist to explain ligand activity in a number of physiological processes. Experimental ... Continue Reading