ABSTRACT: Background Alzheimer's disease (AD) brain shows an ongoing inflammatory condition and non-steroidal anti-inflammatories diminish the risk of suffering the neurologic disease. Cannabinoids are neuroprotective and anti-inflammatory agents with therapeutic potential. Methods We have studied the effects of prolonged oral administration of transgenic amyloid ... Continue Reading
Alzheimer’s Disease
Calming Effect of Medical Cannabis Can Save Lives
In a new study, medical cannabis has been shown to bring emotional relief to Alzheimer patients, thereby reducing the complications caused by this neurological disease. This post from The Open Mind highlights the findings of the research. Scientific research continues to uncover an astonishing number of ways in which medical cannabis can treat human ailments. The latest is a ... Continue Reading
STUDY: Targeting the Endocannabinoid System in Alzheimer’s Disease
ABSTRACT: The endocannabinoid system is rapidly emerging as a potential drug target for a variety of immune-mediated central nervous system diseases. There is a growing body of evidence suggesting that endocannabinoid interventions may have particular relevance to Alzheimer's disease. Here we present a review of endocannabinoid physiology, the evidence that underscores its ... Continue Reading
STUDY: Multi-Target-Directed Ligands and other Therapeutic Strategies in the Search of a Real Solution for Alzheimer’s Disease
ABSTRACT: The lack of an adequate therapy for Alzheimer's Disease (AD) contributes greatly to the continuous growing amount of papers and reviews, reflecting the important efforts made by scientists in this field. It is well known that AD is the most common cause of dementia, and up-to-date there is no prevention therapy and no cure for the disease, which contrasts with the ... Continue Reading
STUDY: Emerging Role of the CB2 Cannabinoid Receptor in Immune Regulation and Therapeutic Prospects
ABSTRACT: There is now a large body of data that indicates that the CB2 cannabinoid receptor type 2 (CB2) is linked to a variety of immune functional events. This functional relevance appears to be most salient in the course of inflammation, a process during which there is an increased number of receptors that are available for activation. Studies aimed at elucidating signal ... Continue Reading