ABSTRACT: The cannabinoid receptor 1 (CB1) and CB2 cannabinoid receptors, associated with drugs of abuse, may provide a means to treat pain, mood, and addiction disorders affecting widespread segments of society. Whether the orphan G-protein coupled receptor GPR55 is also a cannabinoid receptor remains unclear as a result of conflicting pharmacological studies. GPR55 has ... Continue Reading
pain
How Medical Cannabis Can Help Arthritis
Medical cannabis, with its anti-inflammatory properties and without the side effects of opiate use, is gaining popularity as a treatment for arthritis. This post from Leafly gives a low-down on the role medical cannabis can play in dealing with arthritis. It’s no secret: America’s baby boomers are aging, and one of the most common ailments in older populations is arthritis. ... Continue Reading
STUDY: 20. Integrating Cannabis Into Clinical Care
ABSTRACT: Focus Areas: Integrative Approaches to Care, Mental Health, Alleviating Pain Cannabis is now available to patients as a medicine in 18 states and the District of Columbia. Unfortunately, due to the long-standing prohibition, most providers have little information regarding the medicinal use of this versatile botanical. The history of cannabis as medicine will be ... Continue Reading
STUDY: Evaluation of Phytocannabinoids from High Potency Cannabis sativa using In Vitro Bioassays to Determine Structure-Activity Relationships for Cannabinoid Receptor 1 and Cannabinoid Receptor 2
ABSTRACT: Cannabis has been around for thousands of years and has been used recreationally, medicinally, and for fiber. Over 500 compounds have been isolated from Cannabis sativawith approximately 105 being cannabinoids. Of those 105 compounds, Δ9-tetrahydrocannabinol has been determined as the primary constituent, which is also responsible for the psychoactivity associated ... Continue Reading
Cannabis Use for Chronic Pain Has a Reasonable Safety Profile
Medical cannabis, when used by cannabis-experienced chronic pain patients for over a year, was found to have a reasonable safety profile. This post from Futurity reviews the finding of the study conducted at McGill University on 215 adult chronic pain patients along with a control group of 216 patients. Patients with chronic pain who used cannabis daily for one year did not ... Continue Reading