ABSTRACT: Background Cervical cancer remains a global health related issue among females of Sub-Saharan Africa, with over half a million new cases reported each year. Different therapeutic regimens have been suggested in various regions of Africa, however, over a quarter of a million women die of cervical cancer, annually. This makes it the most lethal cancer amongst black ... Continue Reading
apoptosis
CBD Kills Breast Cancer Cells, Minimal Harm to Healthy Cells
A study has found that CBD inflicts programmed cell death in breast cancer cells, leaving the healthy cells unharmed. This post from Reset.Me adds anticancer properties to CBD’s long list of medicinal qualities. Cannabidiol (CBD) — a non-psychoactive phytocannabinoid derived from the cannabis plant — is gaining traction in medical circles and the public eye as increasing ... Continue Reading
STUDY: Cannabinoid 1 receptor activation contributes to vascular inflammation and cell death in a mouse model of diabetic retinopathy and a human retinal cell line
ABSTRACT: Aims/hypothesis Recent studies have demonstrated that cannabinoid-1 (CB1) receptor blockade ameliorated inflammation, endothelial and/or cardiac dysfunction, and cell death in models of nephropathy, atherosclerosis and cardiomyopathy. However the role of CB1receptor signalling in diabetic retinopathy remains unexplored. Using genetic deletion or pharmacological ... Continue Reading
STUDY: Cannabinoid 1 receptor activation contributes to vascular inflammation and cell death in a mouse model of diabetic retinopathy and a human retinal cell line
ABSTRACT: Aims/hypothesis Recent studies have demonstrated that cannabinoid-1 (CB1) receptor blockade ameliorated inflammation, endothelial and/or cardiac dysfunction, and cell death in models of nephropathy, atherosclerosis and cardiomyopathy. However the role of CB1receptor signalling in diabetic retinopathy remains unexplored. Using genetic deletion or pharmacological ... Continue Reading
STUDY: Head Injury – N-arachidonoyl–serine is neuroprotective after traumatic brain injury by reducing apoptosis
ABSTRACT: N-arachidonoyl--serine (AraS) is a brain component structurally related to the endocannabinoid family. We investigated the neuroprotective effects of AraS following closed head injury induced by weight drop onto the exposed fronto-parietal skull and the mechanisms involved. A single injection of AraS following injury led to a significant improvement in functional ... Continue Reading