ABSTRACT: Over the past few years, increasing public and political pressure has supported legalization of medical marijuana. One of the main thrusts in this effort has related to the treatment of refractory epilepsy—especially in children with Dravet syndrome—using cannabidiol (CBD). Despite initiatives in numerous states to at least legalize possession of CBD oil for treating ... Continue Reading
Epilepsy
STUDY: Anxiety – Cannabidiol in Humans—The Quest for Therapeutic Targets
ABSTRACT: Cannabidiol (CBD), a major phytocannabinoid constituent of cannabis, is attracting growing attention in medicine for its anxiolytic, antipsychotic, antiemetic and anti-inflammatory properties. However, up to this point, a comprehensive literature review of the effects of CBD in humans is lacking. The aim of the present systematic review is to examine the randomized ... Continue Reading
CBD Treatment for Seizures to Begin for Girl Who Inspired Carly’s Law
In this post from AL.com, Martin J. Reed reports that Carly Chandler, the young girl who inspired Carly’s Law is expected to soon receive her first treatment of cannabidiol. One of the latest patients to begin the University of Alabama at Birmingham's study known as Carly's Law that uses a marijuana-derived medication to treat severe seizures is the young girl who inspired the ... Continue Reading
New Study Finds Epilepsy Patients Benefiting From Cannabidiol
In this post from Digital Journal, Tim Sandle reports a new research that indicates that cannabidiol can reduce the frequency of seizures, and even halt them, in patients suffering from two rare forms of epilepsy. The new research indicates that cannabidiol, one of dozens of active cannabinoids found in the marijuana plant, can reduce the frequency of seizures in patients ... Continue Reading
STUDY: Seizure – Cannabidivarin-rich cannabis extracts are anticonvulsant in mouse and rat via a CB1 receptor-independent mechanism
ABSTRACT: BACKGROUND AND PURPOSE Epilepsy is the most prevalent neurological disease and is characterized by recurrent seizures. Here, we investigate (i) the anticonvulsant profiles of cannabis-derived botanical drug substances (BDSs) rich in cannabidivarin (CBDV) and containing cannabidiol (CBD) in acute in vivo seizure models and (ii) the binding of CBDV BDSs and their ... Continue Reading