ABSTRACT: Schizophrenia is a complex mental health disorder with positive, negative and cognitive symptom domains. Approximately one third of patients are resistant to currently available medication. New therapeutic targets and a better understanding of the basic biological processes that drive pathogenesis are needed in order to develop therapies that will improve quality ... Continue Reading
psychosis
STUDY: Association between cannabis use, psychosis, and schizotypal personality disorder: findings from the National Epidemiologic Survey of Alcohol and Related Conditions
ABSTRACT: Background Studies to date showing an association between cannabis use and schizophrenia-spectrum disorders are of relatively small sample sizes with limitations in generalizability. The present study addresses this gap by examining the relationship between cannabis use and psychotic-like symptoms in a large representative community sample. Method Data ... Continue Reading
STUDY: Cannabis—A Valuable Drug That Deserves Better Treatment
ABSTRACT: About 150 years ago, a French psychiatrist, J. J. Moreau, conducted a novel clinicalEXPERIMENT in which he administered hashish to humans. His volunteers, including Moreau himself, experienced “occurrences of delirium or of actual madness. …” He concluded that “There is not a single, elementary manifestation of mental illness that cannot be found in the mental ... Continue Reading
STUDY: Adolescent cannabis use and psychosis: epidemiology and neurodevelopmental models
ABSTRACT: Cannabis is one of the most widely used illicit drugs among adolescents, and most users firstEXPERIMENT with it in adolescence. Adolescence is a critical phase for brain development, characterized by neuronal maturation and rearrangement processes, such as myelination, synaptic pruning and dendritic plasticity. The endocannabinoid system plays an important role in ... Continue Reading
STUDY: Anxiety – Pharmacological interventions in the treatment of the acute effects of cannabis: a systematic review of literature
ABSTRACT: Background Cannabis intoxication is related to a number of physical and mental health risks with ensuing social costs. However, little attention has been given to the investigation of possible pharmacological interactions in this condition. Objective To review the available scientific literature concerning pharmacological interventions for the treatment of ... Continue Reading